UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation, and biological properties.

نویسندگان

  • M Ueki
  • K Abe
  • M Hanafi
  • K Shibata
  • T Tanaka
  • M Taniguchi
چکیده

Novel antifungal antibiotics, UK-2A, B and a mixture of C and D, were obtained from the mycelial cake of Streptomyces sp. 517-02. All of the UK-2 compounds were similar in structure to antimycin A. The antifungal activities of UK-2 compounds were as strong as that of antimycin A. However, the UK-2 compounds demonstrated weak cytotoxicity compared to antimycin A.

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UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. VI(1). Structure-activity relationships of UK-2A.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 49 7  شماره 

صفحات  -

تاریخ انتشار 1996